Antibiotic Drugs are used to cure or eliminate certain forms of bacterial infections. They work by either destroying bacteria or blocking their reproduction and spreading. Antibiotics must be administered and used properly to help avoid the spread of antibiotic resistance. This occurs when a bacterial strain no longer reacts to treatment with one or more antibiotics. Antibiotic Drugs are often prescribed only for more acute bacterial infections, since certain infections resolve on their own. Antibiotics must be used correctly in order to help mitigate antibiotic resistance. Antibiotics become less successful as bacteria become immune to them over time.